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NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ

Protein kinase C-θ (PKCθ) is a Ca(2+)-independent member of the PKC family that is selectively expressed in skeletal muscle and T lymphocytes and plays an important role in T cell activation. However, the molecular basis for the important functions of PKCθ in T cells and the manner in which it becom...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Coudronniere, Nolwenn, Villalba, Martin, Englund, Nathan, Altman, Amnon
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716728/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060028097
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