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Expansion of human SCID-repopulating cells under hypoxic conditions

It has been proposed that bone marrow (BM) hematopoietic stem and progenitor cells are distributed along an oxygen (O(2)) gradient, where stem cells reside in the most hypoxic areas and proliferating progenitors are found in O(2)-rich areas. However, the effects of hypoxia on human hematopoietic ste...

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Autori principali: Danet, Guénahel H., Pan, Yi, Luongo, Jennifer L., Bonnet, Dominique A., Simon, M. Celeste
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC162287/
https://ncbi.nlm.nih.gov/pubmed/12840067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317669
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