Expansion of human SCID-repopulating cells under hypoxic conditions

It has been proposed that bone marrow (BM) hematopoietic stem and progenitor cells are distributed along an oxygen (O(2)) gradient, where stem cells reside in the most hypoxic areas and proliferating progenitors are found in O(2)-rich areas. However, the effects of hypoxia on human hematopoietic ste...

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Hlavní autoři: Danet, Guénahel H., Pan, Yi, Luongo, Jennifer L., Bonnet, Dominique A., Simon, M. Celeste
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC162287/
https://ncbi.nlm.nih.gov/pubmed/12840067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317669
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