Expansion of human SCID-repopulating cells under hypoxic conditions

It has been proposed that bone marrow (BM) hematopoietic stem and progenitor cells are distributed along an oxygen (O(2)) gradient, where stem cells reside in the most hypoxic areas and proliferating progenitors are found in O(2)-rich areas. However, the effects of hypoxia on human hematopoietic ste...

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izdano v:	J Clin Invest
Principais autores:	Danet, Guénahel H., Pan, Yi, Luongo, Jennifer L., Bonnet, Dominique A., Simon, M. Celeste
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 2003
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12840067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17669
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