Memory CD4(+) T cells do not induce graft-versus-host disease

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality in allogeneic stem cell transplantation (alloSCT). Donor T cells that accompany stem cell grafts cause GVHD by attacking recipient tissues; therefore, all patients receive GVHD prophylaxis by depletion of T cells from...

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Autores principales: Anderson, Britt E., McNiff, Jennifer, Yan, Jun, Doyle, Hester, Mamula, Mark, Shlomchik, Mark J., Shlomchik, Warren D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC162285/
https://ncbi.nlm.nih.gov/pubmed/12840064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317601
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