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Neuropathy target esterase catalyzes osmoprotective renal synthesis of glycerophosphocholine in response to high NaCl

Glycerophosphocholine (GPC) is an osmoprotective compatible and counteracting organic osmolyte that accumulates in renal inner medullary cells in response to high NaCl and urea. We previously found that high NaCl increases GPC in renal [Madin–Darby canine kidney (MDCK)] cells. The GPC is derived fro...

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Detalhes bibliográficos
Main Authors: Gallazzini, Morgan, Ferraris, Joan D., Kunin, Margarita, Morris, Ryan G., Burg, Maurice B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622810/
https://ncbi.nlm.nih.gov/pubmed/17015841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607133103
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