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GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC

Glycerophosphocholine (GPC) is an abundant osmoprotective renal medullary organic osmolyte. We previously found that its synthesis from phosphatidylcholine is catalyzed by tonicity-regulated activity of the phospholipase B, neuropathy target esterase. We also found that its degradation is catalyzed...

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Détails bibliographiques
Auteurs principaux: Gallazzini, Morgan, Ferraris, Joan D., Burg, Maurice B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504799/
https://ncbi.nlm.nih.gov/pubmed/18667693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805496105
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