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Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism

Altered metabolism of the inositol sugars myo-inositol (MI) and d-chiro-inositol is implicated in diabetic complications. In animals, catabolism of MI and d-chiro-inositol depends on the enzyme MI oxygenase (MIOX), which catalyzes the first committed step of the glucuronate–xylulose pathway, and is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Brown, Peter M., Caradoc-Davies, Tom T., Dickson, James M. J., Cooper, Garth J. S., Loomes, Kerry M., Baker, Edward N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622774/
https://ncbi.nlm.nih.gov/pubmed/17012379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605143103
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