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Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase

Myo-inositol oxygenase (MIOX) catalyzes the novel oxidative cleavage of myo-inositol (MI) and its epimer d-chiro inositol (DCI) to d-glucuronate. MIOX utilizes an Fe(II)/Fe(III) binuclear iron centre for the dioxygen-dependent cleavage of the C1—C6 bond in MI. Despite its key role in inositol metabo...

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Main Authors: Brown, Peter M., Caradoc-Davies, Tom T., Dickson, James M., Cooper, Garth J. S., Loomes, Kerry M., Baker, Edward N.
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242914/
https://ncbi.nlm.nih.gov/pubmed/16880565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106028144
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