G protein-coupled receptors regulate Na(+),K(+)-ATPase activity and endocytosis by modulating the recruitment of adaptor protein 2 and clathrin
Inhibition of Na(+),K(+)-ATPase (NKA) activity in renal epithelial cells by activation of G protein-coupled receptors is mediated by phosphorylation of the catalytic α-subunit followed by endocytosis of active molecules. We examined whether agonists that counteract this effect do so by dephosphoryla...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2000
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060025597 |
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