Affinity purification mass spectrometry characterisation of the interactome of receptor tyrosine kinase proline-rich motifs in cancer

Receptor tyrosine kinase (RTK) overexpression is linked to the development and progression of multiple cancers. RTKs are classically considered to initiate cytoplasmic signalling pathways via ligand-induced tyrosine phosphorylation, however recent evidence points to a second tier of signalling conti...

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Autors principals:	Christopher M. Jones, Arndt Rohwedder, Kin Man Suen, Safoura Zahed Mohajerani, Antonio N. Calabrese, Sabine Knipp, Mark T. Bedford, John E. Ladbury
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-08-01
Col·lecció:	Heliyon
Matèries:	Receptor tyrosine kinase (RTK) SRC homology domain 3 (SH3) SRC homology domain 2 (SH2) Proline-rich motif (PRM) Cancer
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405844024115113
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