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Nitric Oxide Increases the Decay of Matrix Metalloproteinase 9 mRNA by Inhibiting the Expression of mRNA-Stabilizing Factor HuR

Dysregulation of extracellular matrix turnover is an important feature of many inflammatory processes. Rat renal mesangial cells express high levels of matrix metalloproteinase 9 (MMP-9) in response to inflammatory cytokines such as interleukin-1 beta. We demonstrate that NO does strongly destabiliz...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Akool, El-Sayed, Kleinert, Hartmut, Hamada, Farid M. A., Abdelwahab, Mohamed H., Förstermann, Ulrich, Pfeilschifter, Josef, Eberhardt, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12832476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.14.4901-4916.2003
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