The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Abstract GGH (Gamma‐glutamyl hydrolase) is a folate metabolism enzyme that hydrolyzes intracellular polyglutamylated folates and is highly expressed in various cancers. It remains unclear whether GGH functions as an oncogene and its underlying mechanisms in tumor progression. Here, it is reported th...

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Hlavní autoři:	Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-11-01
Edice:	Advanced Science
Témata:	GGH HuR RNA‐binding protein mRNA stability lung cancer
On-line přístup:	https://doi.org/10.1002/advs.202500838
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