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Rapid Deadenylation Triggered by a Nonsense Codon Precedes Decay of the RNA Body in a Mammalian Cytoplasmic Nonsense-Mediated Decay Pathway

Nonsense-mediated mRNA decay (NMD) is an RNA surveillance pathway that detects and destroys aberrant mRNAs containing nonsense or premature termination codons (PTCs) in a translation-dependent manner in eukaryotes. In yeast, the NMD pathway bypasses the deadenylation step and directly targets PTC-co...

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Bibliografiset tiedot
Päätekijät: Chen, Chyi-Ying A., Shyu, Ann-Bin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC162215/
https://ncbi.nlm.nih.gov/pubmed/12832468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.4805-4813.2003
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