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Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

Summary: The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA splicing activation, repression, export, stabilization, and translation. SR-splicing factor 5 (SRSF5) is a glucose-inducible protein that promotes tumor cell growth. However, the functional role of SRSF5...

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Principais autores: Xiaoli Zhang, Ze Wang, Qing Xu, Yuhan Chen, Wen Liu, Tong Zhong, Hongchang Li, Chengshi Quan, Lingqiang Zhang, Chun-Ping Cui
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-10-01
Serier:iScience
Fag:
Molecular physiology
Molecular biology
Molecular mechanism of gene regulation
Transcriptomics
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004221010658
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