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HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain

We have isolated the complete coding sequences for two Xenopus laevis isoforms of heterochromatin protein 1, corresponding to HP1α and HP1γ. The sequence of xHP1α shows considerable divergence from its mammalian homologues, whereas xHP1γ is highly conserved. Functionally, xHP1α behaves identically t...

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Bibliografske podrobnosti
Main Authors: Meehan, Richard R., Kao, Cheng-Fu, Pennings, Sari
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC162158/
https://ncbi.nlm.nih.gov/pubmed/12805230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg306
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