Loading...

Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis

Trimethyllysine (Kme3) reader proteins are targets for inhibition due to their role in mediating gene expression. Although all such reader proteins bind Kme3 in an aromatic cage, the driving force for binding may differ; some readers exhibit evidence for cation–π interactions whereas others do not....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Baril, Stefanie A., Koenig, Amber L., Krone, Mackenzie W., Albanese, Katherine I., Qixin He, Cyndi, Lee, Ga Young, Houk, Kendall N., Waters, Marcey L., Brustad, Eric M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040664/
https://ncbi.nlm.nih.gov/pubmed/29111699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09223
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!