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HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain
We have isolated the complete coding sequences for two Xenopus laevis isoforms of heterochromatin protein 1, corresponding to HP1α and HP1γ. The sequence of xHP1α shows considerable divergence from its mammalian homologues, whereas xHP1γ is highly conserved. Functionally, xHP1α behaves identically t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC162158/ https://ncbi.nlm.nih.gov/pubmed/12805230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg306 |
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