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Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers

A method is described to study the precise positioning of transmembrane peptides in a phospholipid bilayer combining hydrogen/deuterium (H/D) exchange and nanoelectrospray ionization mass spectrometry. The method was tested by using model systems consisting of designed α-helical transmembrane peptid...

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Bibliografische gegevens
Hoofdauteurs: Demmers, Jeroen A. A., Haverkamp, Johan, Heck, Albert J. R., Koeppe, Roger E., Killian, J. Antoinette
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16214/
https://ncbi.nlm.nih.gov/pubmed/10725361
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