Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers

A method is described to study the precise positioning of transmembrane peptides in a phospholipid bilayer combining hydrogen/deuterium (H/D) exchange and nanoelectrospray ionization mass spectrometry. The method was tested by using model systems consisting of designed α-helical transmembrane peptid...

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Bibliographic Details
Main Authors: Demmers, Jeroen A. A., Haverkamp, Johan, Heck, Albert J. R., Koeppe, Roger E., Killian, J. Antoinette
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16214/
https://ncbi.nlm.nih.gov/pubmed/10725361
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