Putative Phosphatidylinositol 3-Kinase (PI3K) Binding Motifs in Ovine Betaretrovirus Env Proteins Are Not Essential for Rodent Fibroblast Transformation and PI3K/Akt Activation

Jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) are simple betaretroviruses that cause epithelial cell tumors in the lower and upper airways of sheep and goats. The envelope (Env) glycoproteins of both viruses can transform rodent and chicken fibroblasts, indicating that the...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Liu, Shan-Lu, Lerman, Michael I., Miller, A. Dusty
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Transformation and Oncogenesis
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12829832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.14.7924-7935.2003
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