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Putative Phosphatidylinositol 3-Kinase (PI3K) Binding Motifs in Ovine Betaretrovirus Env Proteins Are Not Essential for Rodent Fibroblast Transformation and PI3K/Akt Activation

Jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) are simple betaretroviruses that cause epithelial cell tumors in the lower and upper airways of sheep and goats. The envelope (Env) glycoproteins of both viruses can transform rodent and chicken fibroblasts, indicating that the...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Liu, Shan-Lu, Lerman, Michael I., Miller, A. Dusty
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12829832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.14.7924-7935.2003
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