Putative Phosphatidylinositol 3-Kinase (PI3K) Binding Motifs in Ovine Betaretrovirus Env Proteins Are Not Essential for Rodent Fibroblast Transformation and PI3K/Akt Activation

Jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) are simple betaretroviruses that cause epithelial cell tumors in the lower and upper airways of sheep and goats. The envelope (Env) glycoproteins of both viruses can transform rodent and chicken fibroblasts, indicating that the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Shan-Lu, Lerman, Michael I., Miller, A. Dusty
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Transformation and Oncogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC161958/
https://ncbi.nlm.nih.gov/pubmed/12829832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7924-7935.2003
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