Prion Replication Alters the Distribution of Synaptophysin and Caveolin 1 in Neuronal Lipid Rafts

The main event in the pathogenesis of prion diseases is the conversion of the cellular prion protein (PrP(C)) into the abnormal, protease-resistant prion protein (PrP(res)). PrP(C) is a GPI-anchored protein located in lipid rafts or detergent-resistant membranes (DRMs). Here we describe the associat...

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Bibliographic Details
Main Authors: Russelakis-Carneiro, Milene, Hetz, Claudio, Maundrell, Kinsey, Soto, Claudio
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618653/
https://ncbi.nlm.nih.gov/pubmed/15509552
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