The Oncogenic Activity of RET Point Mutants for Follicular Thyroid Cells May Account for the Occurrence of Papillary Thyroid Carcinoma in Patients Affected by Familial Medullary Thyroid Carcinoma

Activating germ-line point mutations in the RET receptor are responsible for multiple endocrine neoplasia type 2-associated medullary thyroid carcinoma (MTC), whereas somatic RET rearrangements are prevalent in papillary thyroid carcinomas (PTCs). Some rare kindreds, carrying point mutations in RET,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Melillo, Rosa Marina, Cirafici, Anna Maria, De Falco, Valentina, Bellantoni, Marie, Chiappetta, Gennaro, Fusco, Alfredo, Carlomagno, Francesca, Picascia, Antonella, Tramontano, Donatella, Tallini, Giovanni, Santoro, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2004
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618571/
https://ncbi.nlm.nih.gov/pubmed/15277225
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky