Mostly Separate Distributions of CLAC- versus Aβ40- or Thioflavin S-Reactivities in Senile Plaques Reveal Two Distinct Subpopulations of β-Amyloid Deposits

Collagenous Alzheimer amyloid plaque component (CLAC) is a unique non-Aβ amyloid component of senile plaques (SP) derived from a transmembrane collagen termed CLAC-precursor. Here we characterize the chronological and spatial relationship of CLAC with other features of SP amyloid in the brains of pa...

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Detalhes bibliográficos
Main Authors: Kowa, Hisatomo, Sakakura, Tomoko, Matsuura, Yusuke, Wakabayashi, Tomoko, Mann, David M.A., Duff, Karen, Tsuji, Shoji, Hashimoto, Tadafumi, Iwatsubo, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618534/
https://ncbi.nlm.nih.gov/pubmed/15215182
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