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Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2
The tyrosine kinase, Janus kinase-2 (Jak2), plays a pivotal role in signal transduction through a variety of cytokine receptors, including the receptor for erythropoietin (Epo). Although the physiological relevance of Jak2 has been definitively established, less is known about its regulation. In stu...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1618111/ https://ncbi.nlm.nih.gov/pubmed/17024180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601365 |
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