RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

While the interferon (IFN)–inducible double-stranded RNA (dsRNA)–dependent protein kinase PKR is reported to initiate apoptosis in some instances, the mechanism by which diverse stress stimuli activate PKR remains unknown. Now we report that RAX, the only known cellular activator for PKR, initiates...

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Detalhes bibliográficos
Main Authors: Bennett, Richard L., Blalock, William L., Abtahi, Dean M., Pan, Yu, Moyer, Sue A., May, W. Stratford
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Chemokines, Cytokines, and Interleukins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617065/
https://ncbi.nlm.nih.gov/pubmed/16861340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-006817
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