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High-throughput assays for DNA gyrase and other topoisomerases
We have developed high-throughput microtitre plate-based assays for DNA gyrase and other DNA topoisomerases. These assays exploit the fact that negatively supercoiled plasmids form intermolecular triplexes more efficiently than when they are relaxed. Two assays are presented, one using capture of a...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1616945/ https://ncbi.nlm.nih.gov/pubmed/16936317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl504 |
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