12/15-Lipoxygenase Is Increased in Alzheimer’s Disease: Possible Involvement in Brain Oxidative Stress

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that impairs cognition and behavior. Although the initiating molecular events are not known, increasing evidence suggests that oxidative stress could play a functional role in its pathogenesis. Lipoxygenase (LOX) enzymes by oxidizing p...

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Autores principales: Praticò, Domenico, Zhukareva, Victoria, Yao, Yuemang, Uryu, Kunihiro, Funk, Colin D., Lawson, John A., Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2004
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615676/
https://ncbi.nlm.nih.gov/pubmed/15111312
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