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Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis
Oxidative stress is a key feature in the Alzheimer's disease (AD) brain and manifests as lipid peroxidation (LPO). Isoprostanes (iPs) are specific and sensitive markers of in vivo LPO. To determine whether amyloid β (Aβ) deposition in vivois associated with increased LPO, we examined iP levels...
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| Vydáno v: | J Neurosci |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762743/ https://ncbi.nlm.nih.gov/pubmed/11404403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-12-04183.2001 |
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