Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation

In a strategy to specifically target complement inhibitors to sites of complement activation and disease, recombinant fusion proteins consisting of a complement inhibitor linked to a C3 binding region of complement receptor (CR) 2 were prepared and characterized. Natural ligands for CR2 are C3 break...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Song, Hongbin, He, Chun, Knaak, Christian, Guthridge, Joel M., Holers, V. Michael, Tomlinson, Stephen
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 2003
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161422/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12813023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17348
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