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Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation

In a strategy to specifically target complement inhibitors to sites of complement activation and disease, recombinant fusion proteins consisting of a complement inhibitor linked to a C3 binding region of complement receptor (CR) 2 were prepared and characterized. Natural ligands for CR2 are C3 break...

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Autors principals: Song, Hongbin, He, Chun, Knaak, Christian, Guthridge, Joel M., Holers, V. Michael, Tomlinson, Stephen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC161422/
https://ncbi.nlm.nih.gov/pubmed/12813023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317348
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