Creutzfeldt-Jakob Disease (CJD) with a Mutation at Codon 148 of Prion Protein Gene : Relationship with Sporadic CJD

Creutzfeldt-Jakob disease (CJD), the most common human prion disease, includes sporadic (s) and familial (f) forms. Regardless of etiology, both forms are thought to share the pathogenic mechanism whereby the cellular prion protein (PrP(C)) converts into its pathogenic isoform (PrP(Sc)). While PrP(C...

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Bibliografski detalji
Glavni autori: Pastore, Manuela, Chin, Steven S., Bell, Karen L., Dong, Zhiqian, Yang, Qiwei, Yang, Lizhu, Yuan, Jue, Chen, Shu G., Gambetti, Pierluigi, Zou, Wen-Quan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2005
Teme:
Original Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613192/
https://ncbi.nlm.nih.gov/pubmed/16314483
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