Creutzfeldt-Jakob Disease (CJD) with a Mutation at Codon 148 of Prion Protein Gene : Relationship with Sporadic CJD

Creutzfeldt-Jakob disease (CJD), the most common human prion disease, includes sporadic (s) and familial (f) forms. Regardless of etiology, both forms are thought to share the pathogenic mechanism whereby the cellular prion protein (PrP(C)) converts into its pathogenic isoform (PrP(Sc)). While PrP(C...

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Detalhes bibliográficos
Main Authors: Pastore, Manuela, Chin, Steven S., Bell, Karen L., Dong, Zhiqian, Yang, Qiwei, Yang, Lizhu, Yuan, Jue, Chen, Shu G., Gambetti, Pierluigi, Zou, Wen-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613192/
https://ncbi.nlm.nih.gov/pubmed/16314483
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