Participation of Autophagy in Storage of Lysosomes in Neurons from Mouse Models of Neuronal Ceroid-Lipofuscinoses (Batten Disease)

In cathepsin D-deficient (CD−/−) and cathepsins B and L double-deficient (CB−/−CL−/−) mice, abnormal vacuolar structures accumulate in neurons of the brains. Many of these structures resemble autophagosomes in which part of the cytoplasm is retained but their precise nature and biogenesis remain unk...

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Библиографические подробности
Главные авторы: Koike, Masato, Shibata, Masahiro, Waguri, Satoshi, Yoshimura, Kentaro, Tanida, Isei, Kominami, Eiki, Gotow, Takahiro, Peters, Christoph, von Figura, Kurt, Mizushima, Noboru, Saftig, Paul, Uchiyama, Yasuo
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2005
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Original Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613187/
https://ncbi.nlm.nih.gov/pubmed/16314482
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