Development of a Human Immunodeficiency Virus Vector-Based, Single-Cycle Assay for Evaluation of Anti-Integrase Compounds

Therapeutic strategies aimed at inhibiting human immunodeficiency virus type 1 (HIV-1) replication employ a combination of drugs targeted to two viral enzymes (reverse transcriptase and protease) and to the viral entry/fusion step. However, the high propensity of HIV-1 to develop resistance makes th...

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Bibliografiske detaljer
Main Authors: Bona, Roberta, Andreotti, Mauro, Buffa, Viviana, Leone, Pasqualina, Galluzzo, Clementina Maria, Amici, Roberta, Palmisano, Lucia, Mancini, Maria Grazia, Michelini, Zuleika, Di Santo, Roberto, Costi, Roberta, Roux, Alessandra, Pommier, Yves, Marchand, Christophe, Vella, Stefano, Cara, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610086/
https://ncbi.nlm.nih.gov/pubmed/17005823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00517-06
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