Decreased Collagen Production in Chronologically Aged Skin : Roles of Age-Dependent Alteration in Fibroblast Function and Defective Mechanical Stimulation

Reduced synthesis of collagen types I and III is characteristic of chronologically aged skin. The present report provides evidence that both cellular fibroblast aging and defective mechanical stimulation in the aged tissue contribute to reduced collagen synthesis. The reduction in collagen synthesis...

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Bibliografische gegevens
Hoofdauteurs: Varani, James, Dame, Michael K., Rittie, Laure, Fligiel, Suzanne E.G., Kang, Sewon, Fisher, Gary J., Voorhees, John J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2006
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Regular Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606623/
https://ncbi.nlm.nih.gov/pubmed/16723701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051302
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