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Decreased Collagen Production in Chronologically Aged Skin : Roles of Age-Dependent Alteration in Fibroblast Function and Defective Mechanical Stimulation

Reduced synthesis of collagen types I and III is characteristic of chronologically aged skin. The present report provides evidence that both cellular fibroblast aging and defective mechanical stimulation in the aged tissue contribute to reduced collagen synthesis. The reduction in collagen synthesis...

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Detalhes bibliográficos
Main Authors: Varani, James, Dame, Michael K., Rittie, Laure, Fligiel, Suzanne E.G., Kang, Sewon, Fisher, Gary J., Voorhees, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606623/
https://ncbi.nlm.nih.gov/pubmed/16723701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051302
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