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β-Amyloid Mediated Nitration of Manganese Superoxide Dismutase : Implication for Oxidative Stress in a APP(NLh/NLh) X PS-1(P264L/P264L) Double Knock-In Mouse Model of Alzheimer’s Disease
Alzheimer’s disease is a multifactorial, progressive, age-related neurodegenerative disease. In familial Alzheimer’s disease, Aβ is excessively produced and deposited because of mutations in the amyloid precursor protein, presenilin-1, and presenilin-2 genes. Here, we generated a double homozygous k...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Investigative Pathology
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1606606/ https://ncbi.nlm.nih.gov/pubmed/16651627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051223 |
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