Detection and Localization of PrP(Sc) in the Skeletal Muscle of Patients with Variant, Iatrogenic, and Sporadic Forms of Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob disease (vCJD) differs from other human prion diseases in that the pathogenic prion protein PrP(Sc) can be detected to a greater extent at extraneuronal sites throughout the body, principally within lymphoid tissues. However, a recent study using a high-sensitivity Western...

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Bibliografiske detaljer
Main Authors: Peden, Alexander H., Ritchie, Diane L., Head, Mark W., Ironside, James W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606529/
https://ncbi.nlm.nih.gov/pubmed/16507908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050788
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