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Analysis of Prion Strains by PrP(Sc) Profiling in Sporadic Creutzfeldt–Jakob Disease
BACKGROUND: Prion diseases are a group of invariably fatal neurodegenerative disorders affecting humans and a wide range of mammals. An essential part of the infectious agent, termed the prion, is composed of an abnormal isoform (PrP(Sc)) of a host-encoded normal cellular protein (PrP(C)). The conve...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316067/ https://ncbi.nlm.nih.gov/pubmed/16354106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030014 |
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