Analysis of Prion Strains by PrP(Sc) Profiling in Sporadic Creutzfeldt–Jakob Disease

BACKGROUND: Prion diseases are a group of invariably fatal neurodegenerative disorders affecting humans and a wide range of mammals. An essential part of the infectious agent, termed the prion, is composed of an abnormal isoform (PrP(Sc)) of a host-encoded normal cellular protein (PrP(C)). The conve...

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Detalhes bibliográficos
Main Authors: Schoch, Gaby, Seeger, Harald, Bogousslavsky, Julien, Tolnay, Markus, Janzer, Robert Charles, Aguzzi, Adriano, Glatzel, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316067/
https://ncbi.nlm.nih.gov/pubmed/16354106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030014
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