Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage

Vascular remodeling in chronic hypoxic pulmonary hypertension includes marked fibroproliferative changes in the pulmonary artery (PA) adventitia. Although resident PA fibroblasts have long been considered the primary contributors to these processes, we tested the hypothesis that hypoxia-induced pulm...

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Autori principali: Frid, Maria G., Brunetti, Jacqueline A., Burke, Danielle L., Carpenter, Todd C., Davie, Neil J., Reeves, John T., Roedersheimer, Mark T., van Rooijen, Nico, Stenmark, Kurt R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2006
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Original Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606508/
https://ncbi.nlm.nih.gov/pubmed/16436679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050599
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