Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage

Vascular remodeling in chronic hypoxic pulmonary hypertension includes marked fibroproliferative changes in the pulmonary artery (PA) adventitia. Although resident PA fibroblasts have long been considered the primary contributors to these processes, we tested the hypothesis that hypoxia-induced pulm...

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Hlavní autoři: Frid, Maria G., Brunetti, Jacqueline A., Burke, Danielle L., Carpenter, Todd C., Davie, Neil J., Reeves, John T., Roedersheimer, Mark T., van Rooijen, Nico, Stenmark, Kurt R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606508/
https://ncbi.nlm.nih.gov/pubmed/16436679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050599
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