Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage

Vascular remodeling in chronic hypoxic pulmonary hypertension includes marked fibroproliferative changes in the pulmonary artery (PA) adventitia. Although resident PA fibroblasts have long been considered the primary contributors to these processes, we tested the hypothesis that hypoxia-induced pulm...

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Bibliografiska uppgifter
Huvudupphovsmän: Frid, Maria G., Brunetti, Jacqueline A., Burke, Danielle L., Carpenter, Todd C., Davie, Neil J., Reeves, John T., Roedersheimer, Mark T., van Rooijen, Nico, Stenmark, Kurt R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2006
Ämnen:
Original Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606508/
https://ncbi.nlm.nih.gov/pubmed/16436679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050599
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