Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage

Vascular remodeling in chronic hypoxic pulmonary hypertension includes marked fibroproliferative changes in the pulmonary artery (PA) adventitia. Although resident PA fibroblasts have long been considered the primary contributors to these processes, we tested the hypothesis that hypoxia-induced pulm...

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Detalhes bibliográficos
Main Authors: Frid, Maria G., Brunetti, Jacqueline A., Burke, Danielle L., Carpenter, Todd C., Davie, Neil J., Reeves, John T., Roedersheimer, Mark T., van Rooijen, Nico, Stenmark, Kurt R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606508/
https://ncbi.nlm.nih.gov/pubmed/16436679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050599
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