Ly6c(+) “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

In a lethal West Nile virus (WNV) model, central nervous system infection triggered a threefold increase in CD45(int)/CD11b(+)/CD11c(−) microglia at days 6–7 postinfection (p.i.). Few microglia were proliferating, suggesting that the increased numbers were derived from a migratory precursor cell. De...

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Detalhes bibliográficos
Main Authors: Getts, Daniel R., Terry, Rachael L., Getts, Meghann Teague, Müller, Marcus, Rana, Sabita, Shrestha, Bimmi, Radford, Jane, Van Rooijen, Nico, Campbell, Iain L., King, Nicholas J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556789/
https://ncbi.nlm.nih.gov/pubmed/18779347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080421
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