Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

Infiltration of Ly6C(hi) monocytes from the blood is a hallmark of viral encephalitis. In mice with lethal encephalitis caused by West Nile virus (WNV), an emerging neurotropic flavivirus, inhibition of Ly6C(hi) monocyte trafficking into the brain by anti-very late antigen (VLA)-4 integrin antibody...

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Detaylı Bibliyografya
Asıl Yazarlar: Getts, Daniel R, Terry, Rachael L, Getts, Meghann Teague, Müller, Marcus, Rana, Sabita, Deffrasnes, Celine, Ashhurst, Thomas Myles, Radford, Jane, Hofer, Markus, Thomas, Shane, Campbell, Iain L, King, Nicholas JC
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Short Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532418/
https://ncbi.nlm.nih.gov/pubmed/23111065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-246
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