Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

Infiltration of Ly6C(hi) monocytes from the blood is a hallmark of viral encephalitis. In mice with lethal encephalitis caused by West Nile virus (WNV), an emerging neurotropic flavivirus, inhibition of Ly6C(hi) monocyte trafficking into the brain by anti-very late antigen (VLA)-4 integrin antibody...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Getts, Daniel R, Terry, Rachael L, Getts, Meghann Teague, Müller, Marcus, Rana, Sabita, Deffrasnes, Celine, Ashhurst, Thomas Myles, Radford, Jane, Hofer, Markus, Thomas, Shane, Campbell, Iain L, King, Nicholas JC
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532418/
https://ncbi.nlm.nih.gov/pubmed/23111065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-246
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars