Matrix Metalloproteinase Dysregulation in the Stria Vascularis of Mice with Alport Syndrome : Implications for Capillary Basement Membrane Pathology

Alport syndrome results from mutations in genes encoding collagen α3(IV), α4(IV), or α5(IV) and is characterized by progressive glomerular disease associated with a high-frequency sensorineural hearing loss. Earlier studies of a gene knockout mouse model for Alport syndrome noted thickening of stria...

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Bibliographic Details
Main Authors: Gratton, Michael Anne, Rao, Velidi H., Meehan, Daniel T., Askew, Charles, Cosgrove, Dominic
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2005
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606400/
https://ncbi.nlm.nih.gov/pubmed/15855646
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