Pericyte Abnormalities Precede Strial Capillary Basement Membrane Thickening in Alport Mice

In 129 Sv autosomal Alport mice, the strial capillary basement membranes (SCBMs) progressively thicken between 5 and 9 weeks of age resulting in a hypoxic microenvironment with metabolic stress and induction of pro-inflammatory cytokines and chemokines. These events occur concomitant with a drop in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hear Res
Prif Awduron: Dufek, Brianna, Meehan, Daniel T., Delimont, Duane, Samuelson, Gina, Madison, Jacob, Shi, Xiourui, Boettcher, Flint, Gratton, Michael Anne, Trosky, Vincent, Cosgrove, Dominic
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491280/
https://ncbi.nlm.nih.gov/pubmed/32234583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2020.107935
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