Integrin αvβ8-Mediated Activation of Transforming Growth Factor-β by Perivascular Astrocytes : An Angiogenic Control Switch

Brain hemorrhage is a severe complication of both neoplastic and nonneoplastic brain disease. Mice deficient in the αvβ8 integrin display defective brain vessel formation resulting in hemorrhage and perinatal death, but the mechanism of brain hemorrhage is unknown. Because the αvβ8 integrin is expre...

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Bibliographische Detailangaben
Hauptverfasser: Cambier, Stephanie, Gline, Stephanie, Mu, Dezhi, Collins, Rodney, Araya, Jun, Dolganov, Gregory, Einheber, Steven, Boudreau, Nancy, Nishimura, Stephen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602409/
https://ncbi.nlm.nih.gov/pubmed/15920172
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