Lack of Tissue Inhibitor of Metalloproteinases-3 Results in an Enhanced Inflammatory Response in Antigen-Induced Arthritis

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is known to inhibit matrix metalloproteinases, aggrecanases, and tumor necrosis factor (TNF)-α-converting enzyme (TACE, ADAM17). These metalloproteases participate in different aspects of joint destruction in inflammatory arthritis. To determine the...

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Bibliografiset tiedot
Päätekijät: Mahmoodi, Mandana, Sahebjam, Solmaz, Smookler, David, Khokha, Rama, Mort, John S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2005
Aiheet:
Original Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602404/
https://ncbi.nlm.nih.gov/pubmed/15920158
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